The James Buchanan Brady Urological Institute
 
 
 
Trinity J. Bivalacqua, M.D, Ph.D Trinity J. Bivalacqua, M.D, Ph.D
Associate Professor of Urology, Surgery, and Oncology
Johns Hopkins Medical Institutions
Director of Urologic Oncology
Johns Hopkins Medical Institutions and Sidney Kimmel Comprehensive Cancer Center (SKCCC)
Associate Program Director Urologic Oncology Fellowship
The James Buchanan Brady Urological Institute

Email:tbivala1@jhmi.edu
         Instructions for patients

RESEARCH ACTIVITES


Free Access to abstracts at PubMed

Publications

  1. H.C. Champion, C.C. Erickson III, M.L. Simoneaux, T.J. Bivalacqua, W.A. Murphy, D.H. Coy and P.J. Kadowitz.  Proadrenomedullin NH2-Terminal 20 Peptide has cAMP-Mediated Activity in the Mesenteric Vascular Bed of the Cat.  Peptides 17:1379-1387, 1996. 


  2. H.C. Champion, J.A. Santiago, M.A. Czapla, T.J. Bivalacqua, C. Ilgenfritz and P.J. Kadowitz.  Comparison of Responses to T-kinin and Bradykinin in the Mesenteric Vascular Bed of the Cat.  Peptides 18:1357-1364, 1997. 


  3. H.C. Champion, T.J. Bivalacqua, D.G. Lambert, S.M. McWilliams, J.E. Zadina, A.J. Kastin and P.J. Kadowitz.  Endomorphin 1 and 2, the Endogenous µ-Opioid Agonists, Produce Biphasic Changes in Systemic Arterial Pressure in the Cat.  Life Science 63:PL131-PL136, 1998.


  4. H.C. Champion, T.J. Bivalacqua, A. Rauchwarger, S.M. McWilliams, D.B. McNamara and P.J. Kadowitz.  Analysis of Vasodepressor Responses of Nociceptin and Nociceptin Analogs in the Systemic Vascular Bed of the Anesthetized Rabbit In VivoJournal of Cardiovascular Pharmacology and Therapeutics 3:247-252, 1998.


  5. T.J. Bivalacqua, M. Rajasekaran, H.C. Champion, R. Wang, S.C. Sikka, P.J. Kadowitz, and W.J.G. Hellstrom.  The Influence of Castration on Pharmacological Induction of Penile Erection in the Cat.  Journal of Andrology 19:551-557, 1998.


  6. H.C. Champion, T.J. Bivalacqua, R. Wang, W.J.G. Hellstrom and P.J. Kadowitz.  [Tyr1]- Nociceptin and Nociceptin have Similar Naloxone-Insensitive Erectile Activity in the Cat.  Journal of Andrology 19:747-753, 1998. 

  7. H.C. Champion, T.J. Bivalacqua, D.E. Friedman, J.E. Zadina, A.J. Kastin, and P.J. Kadowitz.  Nitric Oxide Mediates Vasodilator Response to Endomorphin 1, but Not Nociceptin/OFQ, in the Hindquarters Vascular Bed of the Rat.  Peptides 19:1595-1602, 1998. 


  8. T.J. Bivalacqua, A. Dalal, D.G. Lambert, H.C. Champion, and P.J. Kadowitz.  Effects of Candesartan and PD 123319 on Responses to Angiotensin II in the Anesthetized Mouse.  Journal of American Society of Nephrology 10:S98-S100, 1999.


  9. H.C. Champion, T.J. Bivalacqua, D.L. Lambert, D.B. McNamara, and P.J. Kadowitz.  Analysis of the Effects of Candesartan on Responses to Angiotensin II in the Hindquarters Vascular Bed of the Cat. Journal of American Society of Nephrology 10:S101-S103, 1999. 


  10. H.C. Champion, T.J. Bivalacqua, D.G. Lambert, D.B. McNamara, and P.J. Kadowitz.  The Influence of Candesartan and PD123319 on Responses to Angiotensin II in the Hindquarters Vascular Bed of the Rat. Journal of American Society of Nephrology 10:S95-S97, 1999. 


  11. H.C. Champion, T.J. Bivalacqua, R. Wang, P.J. Kadowitz, L.K. Keefer, J.E. Saavedra,  Hrabie, P.C. Doherty, and W.J.G. Hellstrom. Induction of Penile Erection by Intracavernosal and Transurethral Administration of Novel Nitric Oxide Donors in the Cat.  Journal of Urology 161:2013-2019, 1999. 


  12. H.C. Champion, T.J. Bivalacqua, F.M. D’Souza, L.A. Ortiz, J.R. Jeter, K. Toyoda, D.D. Heistad, A.L. Hyman, and P.J. Kadowitz.  Gene-Transfer of Endothelial Nitric Oxide Synthase to the Lung of the Mouse In Vivo: Effect of Agonist-Induced and Flow-Mediated Responses.  Circulation Research 84:1422-1432, 1999. 


  13. S.K. Ahuja, T.J. Bivalacqua, J. Case, M.J. Vincent, S.C. Sikka, and W.J.G. Hellstrom.  A Pilot Study Demonstrating Clinical Benefit From Intralesional Interferon Alpha-2b in the Treatment of Peyronie’s Disease.  Journal of Andrology 20:444-448, 1999. 


  14. H.C. Champion, T.J. Bivalacqua, A.L. Hyman, L.J. Ignarro, W.J.G. Hellstrom, and P.J. Kadowitz.  Gene Transfer of Endothelial Nitric Oxide Synthase to the Penis Augments Erectile Responses in the Aged Rat.  Proceedings of the National Academy of Science USA 96:11648-11652, 1999.


  15. H.C. Champion, T.J. Bivalacqua, D.G. Lambert, R.A. Abassi, and P.J. Kadowitz.  Analysis of Vasoconstrictor Responses to Histamine in the Hindquarters Vascular Bed of the Rabbit. American Journal of Physiology 277:R1179-R1187, 1999. 


  16. T.J. Bivalacqua, H.C. Champion, M. Rajasekeran, S.C. Sikka, P.J. Kadowitz, P.C. Doherty, and W.J.G. Hellstrom.  Potentiation of Erectile Response and cAMP Accumulation by Combination of Prostaglandin E1 and Rolipram, a Selective Inhibitor of the Type 4 Phosphodiesterase (PDE 4).  Journal of Urology 162:1848-1855, 1999.  


  17. T.J. Bivalacqua, A. Dalal. H.C. Champion, and P.J. Kadowitz.  Role of AT1 Receptors and Autonomic Nervous System in Mediating Acute Pressor Responses to ANG II in Anesthetized Mice. American Journal of Physiology 277:E838-E847, 1999. 


  18. H.C. Champion, T.J. Bivalacqua, J.E. Zadina, A.J. Kastin, and P.J. Kadowitz.  Vasodilator Responses to the Endomorphin Peptides, But Not Nociceptin/OFQ, Are Mediated by Nitric Oxide Release.  Annals of the New York Academy of Sciences 897:165-172, 1999. 


  19. T.J. Bivalacqua, H.C. Champion, R. Wang, P.J. Kadowitz, P.C. Doherty and W.J.G. Hellstrom.  Feline Penile Erection Induced By Transurethral Administration of Sodium Nitroprusside.  Urological Research 27:432-436, 1999. 


  20. H.C. Champion, T.J. Bivalacqua, K. Toyoda, D.D. Heistad, A.L. Hyman, P.J. Kadowitz.  In Vivo Gene-Transfer of Prepro-Calcitonin Gene-Related Peptide to the Lung Attenuates Chronic Hypoxia-Induced Pulmonary Hypertension in the Mouse.  Circulation 101:923-930, 2000.


  21. T.J. Bivalacqua, E.K. Diner, T.E. Novak, Y. Vohra, S.C. Sikka, H.C. Champion, P.J. Kadowitz, and W.J.G. Hellstrom.  A Rat Model of Peyronie’s Disease Associated with a Decrease in Erectile Activity and an Increase in Inducible Nitric Oxide Synthase Protein Expression.  Journal of Urology 163:1992-1998, 2000.


  22. T.J. Bivalacqua, H.C. Champion, S.K. Purohit, W.A. Murphy, D. H. Coy, P.J. Kadowitz and W.J.G. Hellstrom.  Nitric Oxide-Mediated Erectile Effects of Galantide But Not Galanin In Vivo.  Nitric Oxide: Biology and Chemistry 4:94-102, 2000.


  23. M.K. Shah, S.Y. Hugghins, H.C. Champion, and T.J. Bivalacqua.  New Therapies for Treating Hypertension: What Every Physician Should Know.  Journal of the Louisiana State Medical Society 152:334-344, 2000. 


  24. T.J. Bivalacqua, H.C. Champion, Y. S. Mehta, A. B. Abdel-Mageed, L. J. Ignarro, P. J. Kadowitz, and W. J.G. Hellstrom.  Adenoviral Gene Transfer of Endothelial Nitric Oxide Synthase (eNOS) to the Penis Improves Age-Related Erectile Dysfunction in the Rat.  International Journal of Impotence Research 12:S8-S17, 2000.  


  25. M. Burger, S.C. Sikka, T.J. Bivalacqua, D.J. Lamb, and W.J.G. Hellstrom.  The Effect of Sildenafil on Human Sperm Motion and Function From Normal and Infertile Men.  International Journal of Impotence Research 12:229-234, 2000.  


  26. S. Leungwattanakij, T.J. Bivalacqua, J.J. Caulfield, and W.J.G. Hellstrom.  Evaluation of Cadaveric Pericardium in the Rat for the Surgical Treatment of Peyronie’s Disease.  Urology 56:1075-1080, 2000.


  27. G.E. Stanley, T.J. Bivalacqua, and W.J.G. Hellstrom.  Penile Prosthetic Trends in the Era of Effective Oral Erectogenic Agents.  Southern Medical Journal 93:1153-1156, 2000. 


  28. B.J. DeWitt, A.D. Kaye, I.N. Ibrahim, T.J. Bivalacqua, F.M. D’Souza, R.E. Banister, A. Salamarif, and B.B. Nossaman.  Effects of Protein Kinase C Isozyme Inhibitors on Constrictor Responses in the Feline Pulmonary Vascular Bed.  American Journal of Physiology 280:L50-L57, 2001. 


  29. P.C. Doherty, T.J. Bivalacqua, H.C. Champion, P.J. Kadowitz, B. Greenwood-Van Meerveld, I. Berzetei-Gurske, and W.J.G. Hellstrom.  Direct Effects of Selective Type 5 Phosphodiesterase Inhibitors, Alone or in Combination with other Vasodilators, on Erectile Response in the Cat.  Journal of Urology 165:1004-1009, 2001.  


  30. T.J. Bivalacqua, H.C. Champion, S. Leungwattanakij, Dae Yul Yang, Jae-Seog Hyun, A. B. Abdel-Mageed, S.C. Sikka, P.J. Kadowitz, and W.J.G. Hellstrom.  Evaluation of Nitric Oxide Synthase and Arginase in the Induction of a Peyronie’s-Like Condition in the Rat.  Journal of Andrology 22:497-506, 2001. 


  31. T.J. Bivalacqua, W.J.G. Hellstrom, P.J. Kadowitz, and H.C. Champion.  Increased Expression of Arginase II in Human Diabetic Corpus Cavernosum: Role in Diabetic-Associated Erectile Dysfunction.  Biochemical Biophysical Research Communication 283:923-927, 2001.  


  32. S.C. Sikka, H.C. Champion, T.J. Bivalacqua, R. Wang, M. Rajasekaran, B.B. Aggarwal, and W.J.G. Hellstrom.  Role of Genitourinary Inflammation in Infertility: Detrimental Effect of Lipopolysaccharide (LPS) and Interferon-gamma (IFN-γ) on Human Spermatozoa.  International Journal of Andrology 24:136-141, 2001. 


  33. T.J. Bivalacqua, H.C. Champion, B.J. DeWitt, J. E. Saavedra, J. A. Hrabie, L. K. Keefer, and P. J. Kadowitz.  Analysis of Vasodilator Responses to Novel Nitric Oxide Donors in the Hindquarters Vascular Bed of the Cat.  Journal of Cardiovascular Pharmacology 38:120-129, 2001. 


  34. H.C. Champion, R.L. Pierce, T.J. Bivalacqua, W.A. Murphy, D.H. Coy, and P.J. Kadowitz.  Analysis of Responses to hAmylin, hCGRP, and hADM in Isolated Resistance Arteries From the Mesenteric Vascular Bed of the Rat.  Peptides 22:1427-1434, 2001.


  35. A. Choppin, D.R. Blue, S.S. Hegde, D. Gennevois, S.A. McKinnon, A. Mokatrin, T.J. Bivalacqua, and W.J.G. Hellstrom.  Evaluation of Oral RO-70-0004 an a1A-Adrenoceptor Antagonist for the Treatment of Male Erectile Dysfunction.  International Journal of Impotence Research 13:157-161, 2001. 


  36. S. Leungwattanakij, T.J. Bivalacqua, S. Reddy, and W.J.G. Hellstrom.  Long-Term Follow Up on Use of Pericardial Graft in the Surgical Management of Peyronie’s Disease.  International Journal of Impotence Research 13:183-186, 2001. 


  37. M.K. Shah, T.J. Bivalacqua, H.C. Champion, and P.J. Kadowitz.  Vasodilator Responses to ATP and UTP are cAMP Dependent in the Mesenteric Vascular Bed of the Cat.  Journal of Cardiovascular Pharmacology and Therapeutics 6:287-295, 2001.

     
  38. T.J. Bivalacqua, H.C. Champion, A. Abdel-Mageed, P.J. Kadowitz, and W.J.G. Hellstrom.  Gene Transfer Of Prepro-Calcitonin Gene Related Peptide Restores Erectile Function In The Aged Rat.  Biology of Reproduction 65:1371-1377, 2001. 


  39. M.K. Shah, H.C. Champion, T.J. Bivalacqua, and P.J. Kadowitz.  Differential Responses to ATPgammaS in the Mesenteric and Hindlimb Vascular Bed of the Cat.  Life Sciences 69:2561-2571, 2001. 


  40. J.S. Hyun, M. Baig, D.Y. Yang, S. Leungwattanakij, K. Kim, A. Abdel-Mageed, T.J. Bivalacqua, and W.J.G. Hellstrom.  Localization of Peripheral Dopamine D1 and D2 Receptors in Rat and Human Seminal Vesicle.  Journal of Andrology 23:114-120, 2002. 


  41. H.C. Champion, T.J. Bivalacqua, J.E. Zadina, A.J. Kastin, A.L. Hyman, and P.J. Kadowitz.  Role of Nitric Oxide in Mediating Vasodilator Responses to Opioid Peptides in the Rat.  Clinical and Experimental Pharmacology and Physiology 29:229-232, 2002. 


  42. T.J. Bivalacqua, H.C. Champion, D.G. Lambert, and P.J. Kadowitz.  Vasodilator Responses to Adenosine and Hyperemia are Mediated by A1 and A2 Receptors in the Cat Vascular Bed.  American Journal of Physiology 282: R1696-R1709, 2002. 


  43. J.S. Hyun, T.J. Bivalacqua, D.Y. Yang, S. Leungwattanakij, M. Baig, A.Abdel-Mageed, K. Kim, and W.J.G. Hellstrom.  Localization of Peripheral Dopamine D1 and D2 Receptors in Rat Corpus Cavernosum. BJU International 90:105-112, 2002. 


  44. J.S. Armstrong, T.J. Bivalacqua, W. Chamulitratsurnamex, S.C. Sikka, and W.J.G. Hellstrom.  A comparison of the NADPH oxidase in human sperm and white blood cells.  International Journal of Andrology 25:223-229, 2002. 


  45. T.J. Bivalacqua, H.C. Champion, M. K. Shah, B.J. DeWitt, E.W. Inscho, and P.J. Kadowitz. Comparative Responses to a, b-methylene-ATP in Cat Pulmonary, Mesenteric, and Hindlimb Vascular Beds.  Journal of Applied Physiology 93:1287-1295, 2002.  


  46. H.C. Champion, T.J. Bivalacqua, S.S. Greenberg, T.D. Giles, A.L. Hyman, and P.J. Kadowtiz.  Adenoviral Gene Transfer of Endothelial Nitric-Oxide Synthase (eNOS) Partially Restores Normal Pulmonary Arterial Pressure in eNOS-Deficient Mice.  Proceeding of the National Academy of Science USA 99:13248-13253, 2002. 


  47. T.J. Bivalacqua, A.L. Hyman, P.J. Kadowitz, N. Paolocci, D.A. Kass, and H.C. Champion.  Role of Calcitonin Gene-Related Peptide (CGRP) in Chronic Hypoxia-Induced Pulmonary Hypertension in the Mouse.  Influence of Gene Transfer In Vivo.  Regulatory Peptides 108:129-133, 2002. 


  48. S. Das, N. Maulik, D.K. Das, P.J. Kadowitz, and T.J. Bivalacqua.  Cardioprotection with Sildenafil, a Selective Inhibitor of Cyclic 3',5'-monophosphate-specific Phosphodiesterase 5.  Drugs Experimental Clinical Research 28:213-219, 2002.


  49. K. Chitaley, T.J. Bivalacqua, H.C. Champion, M.F. Usta, W.J.G. Hellstrom, T.M. Mills, and R. Clinton-Webb.  Adeno-associated viral gene transfer of dominant negative RhoA enhances erectile function in rats.  Biochemical Biophysical Research Communication 298:427-432, 2002. 


  50. H.C. Champion, T.J. Bivalacqua, R.L. Pierce, W.A. Murphy, D.H. Coy, A.L. Hyman, and P.J. Kadowitz.  Responses to Human CGRP, ADM, and PAMP in Human Thymic Arteries.  American Journal of Physiology: Regulatory Integrative Comparative Physiology 284:R531-R537, 2003. 


  51. M. Passarella, M.F. Usta, T.J. Bivalacqua, W.J.G. Hellstrom, and R. Davis.  Testicular-Sparing Surgery: A Reasonable Option in Selected Patients with Testicular Lesions.  BJU International 91:337-340, 2003. 


  52. W.J.G. Hellstrom, J.S. Hyun, L. Human, J.A. Sanabria, T.J. Bivalacqua, and S. Leungwattanakij.  Antimicrobial activity of antibiotic-soaked, Resist trade mark -coated Bioflex.  International Journal of Impotence Research 15:18-21, 2003. 


  53. T.J. Bivalacqua, J.S. Armstrong, J. Biggerstaff, A.B. Abdel-Mageed, P.J. Kadowitz, W.J.G. Hellstrom, and H.C. Champion.  Gene Transfer of Extracellular SOD to the Penis Reduces Superoxide Anion and Improves Erectile Function in Aged Rats.  American Journal of Physiology: Heart and Circulatory Physiology 284:H1408-H1421, 2003. 


  54. S. Leungwattanakij, T.J. Bivalacqua, M.F. Usta, D.Y. Yang, J.S. Hyun, H.C. Champion, A.B. Abdel-Mageed, and W.J.G. Hellstrom.  Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum.  Journal of Andrology 24:239-245, 2003. 


  55. T.J. Bivalacqua, M.F. Usta, H.C. Champion, D. Adams, D.B. McNamara, A.B. Abdel-Mageed, P.J. Kadowitz, and W.J.G. Hellstrom.  Endothelial Nitric Oxide Synthase Gene Therapy Partially Restores NO Synthesis And Erectile Function In Streptozotocin Diabetic Rats.  Journal of Urology 169:1911-1917, 2003. 


  56. S. Leungwattanakij, T.J. Bivalacqua, D.Y. Yang, J.S. Hyun, and W.J.G. Hellstrom.  Comparison of Cadaveric Pericardial, Dermal, Vein and Gort-Tex Grafts for Tunica Albuginea Substitution Using A Rat Model.  BJU International 92:119-124, 2003. 


  57. M.F. Usta, T.J. Bivalacqua, J.Sanabria, I.T. Koksal, K. Moparty, and W.J.G. Hellstrom.  Patient-Partner Satisfaction and Long Term Results After Surgical Treatment for Peyronie’s Disease.  Urology 62:105-109, 2003.    


  58. S.R. Baber, H.C. Champion, T.J. Bivalacqua, A.L. Hyman, and P.J. Kadowitz.  Role of Cyclooxygenase-2 in the Generation of Vasoactive Prostanoids in the Rat Pulmonary and Systemic Vascular Beds.  Circulation 108:896-901, 2003. 


  59. M.F. Usta, T.J. Bivalacqua, D.Y. Yang, A. Ramanitharan, D.R. Sell, A. Viswanathan, V.M. Monnier, and W.J.G. Hellstrom.  The Protective Effect of Aminoguanidine on Erectile Function in Streptozotocin Diabetic Rats.  Journal of Urology 170:1437-1442, 2003. 


  60. W. Deng, T.J. Bivalacqua, N. Chattergoon, A.L. Hyman, J.R. Jeter, and P.J. Kadowitz.  Adenoviral Gene Transfer of Endothelial Nitric Oxide Synthase: High Level Expression in Ex Vivo Expanded Marrow Stromal Cells.  American Journal of Physiology: Cell Physiology 285:C1322-C1329, 2003.    


  61. B. D. Nossaman, P. A. Dabisch, J. T. Liles, S. R. Baber, H. C. Champion, A. D. Kaye, C.J. Feng, M. Anwar, T. J. Bivalacqua, J. A. Santiago, B. J. De Witt, and P. J. Kadowitz.  Peroxynitrite does not impair pulmonary and systemic vascular responses.  Journal of Applied Physiology 96:455-465, 2004. 


  62. M.F. Usta, T.J. Bivalacqua, G.W. Jabren, L. Myers, J. Sanabria, S.C. Sikka, and W.J.G. Hellstrom.  Relationship Between Severity of Penile Curvature and the Presence of Co-Morbidities in Men with Peyronie’s Disease.  Journal of Urology 171:775-779, 2004. 


  63. G. Dang, R. Matern, T.J. Bivalacqua, S.C. Sikka, and W.J.G. Hellstrom.  Intralesional Interferon Alpha-2B Injections for the Treatment of Peyronie’s Disease.  Southern Medical Journal 97:42-46, 2004.


  64. T.J. Bivalacqua, M.F. Usta, H.C. Champion, S. Leungwattanakij, P.A. Dabisch, D.B. McNamara, P.J. Kadowitz, and W.J.G. Hellstrom.  Effect of Combination Endothelial Nitric Oxide Synthase Gene Therapy and Sildenafil on Erectile Function In Diabetic Rats.  International Journal of Impotence Research 16:21-29, 2004.


  65. M.F. Usta, J. Sanabria, T.J. Bivalacqua, and W.J.G. Hellstrom.  Feline Penile Erections Induced By Topical Glans Penis Application Of Combination Alprostadil And SEPA (TOPIGLAN). International Journal of Impotence Research 16:73-77, 2004.


  66. T.J. Bivalacqua, W. Dang, H.C. Champion, W.J.G. Hellstrom, and P.J. Kadowitz.  Gene Therapy Techniques for the Delivery of Endothelial Nitric Oxide Synthase (eNOS) to the Corpora Cavernosa for Erectile Dysfunction.  Methods in Molecular Biology 279:173-186, 2004.  


  67. T.J. Bivalacqua, H.C. Champion, M.F. Usta, S. Cellek, K.Chitaley, R.C. Webb, R.L. Lewis, T.M. Mills, W.J.G. Hellstrom, and P.J. Kadowitz.  RhoA/Rho-Kinase Suppresses Endothelial Nitric Oxide Synthase in the Penis: Mechanism for Diabetes-Associated Erectile Dysfunction.  Proceeding of the National Academy of Science USA 101:9121-9126, 2004.
  68. M.F. Usta, T.J. Bivalacqua, Z. Tokatli, F. Rivera, K.H. Gulkesen, S.C. Sikka, and W.J.G. Hellstrom.  Stratification of Penile Vascular Pathologies in Patients with Peyronie’s Disease and in Men with Erectile Dysfunction: A Comparative Study.  Journal of Urology 172:259-262, 2004.


  69. M.F. Usta, T.J. Bivalacqua, I.T. Koksal, B. Toptas, S. Surmen, and W.J.G. Hellstrom.  The Protective Effect of Aminoguanidine on Erectile Function in Diabetic Rats is Not Related to the Timing of Treatment.  BJU International 94:429-432, 2004. 


  70. W. Deng, T.J. Bivalacqua, N.N. Chattergoon, J.R. Jeter Jr, P.J. Kadowitz.  Engineering ex vivo-expanded marrow stromal cells to secrete calcitonin gene-related peptide using adenoviral vector.  Stem Cells 22:1279-1291, 2004. 


  71. H.C. Champion, T.J. Bivalacqua, E. Takimoto, D.A. Kass, and A.L. Burnett.  Phosphodiesterase-5A Dysregulation in Penile Erectile Tissue is a Mechanism of Priapism.  Proceeding of the National Academy of Science USA 102:1661-1666, 2005.


  72. I.S. Wittstein, D.R. Thiemann, J.A.C. Lima, K.L Baughman, S.P. Schulman, G. Gerstenblith, K.C. Wu, J.J. Rade, T.J. Bivalacqua, and H.C. Champion.  Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress.  New England Journal of Medicine 352:539-548, 2005.


  73. T.J. Bivalacqua, M.F. Usta, M. Kendirci, L. Pradhan, X. Alvarez, H.C. Champion, P.J. Kadowitz, and W.J.G. Hellstrom.  Superoxide Anion Production in the Rat Penis Impairs Erectile Function in Diabetes: Influence of In Vivo Extracellular Superoxide Dismutase Gene Therapy.  The Journal of Sexual Medicine 2:187-198, 2005.   


  74. S.R. Baber, W. Deng, J. Rodriguez, R.G. Master, T.J. Bivalacqua, A.L. Hyman, and P.J.  Kadowitz.  Vasoactive Prostanoids are Generated from Arachidonic Acid by COX-1 and -2 in the Mouse.  American Journal of Physiology: Heart and Circulatory Physiology 289:H1476-1487, 2005.


  75. M. Kendirci, Z. Zsengeller, T.J. Bivalacqua, S. Gur, M.F. Usta, M. Chen, C. Szabo, and W.J.G. Hellstrom.  Poly(Adenosine Diphosphate-Ribose) Polymerase Inhibition Preserves Erectile Function In Rats After Cavernous Nerve Injury.  Journal of Urology 174:2054-2059, 2005.


  76. M.F. Usta, M. Kendirci, S. Gur, N.A. Foxwell, T.J. Bivalacqua, S. Cellek, and W.J.G. Hellstrom.  The Breakdown of Preformed Advanced Glycation End Products Reverses Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats: Preventive Versus Curative Treatment.  Journal of Sexual Medicine 3:242-252, 2006. 


  77. L. Jin, T. Liu, G.A. Lagoda, H.C. Champion, T.J. Bivalacqua, and A.L. Burnett.  Elevated RhoA/Rho-kinase Activity in Aged Rat Penis: Mechanism for Age-Associated Erectile Dysfunction.  FASEB Journal 20:536-538, 2006.


  78. A.L. Burnett, T.J. Bivalacqua, H.C. Champion, and B. Musicki.  Long-Term Oral Phosphodiesterase 5 Inhibitor Therapy Alleviates Recurrent Priapism.  Urology 67:1043-1048, 2006.


  79. A.L. Burnett, T.J. Bivalacqua, H.C. Champion, and B. Musicki.  Feasibility of the Use of Phosphodiesterase Type 5 Inhibitors in a Pharmacologic Prevention Program for Recurrent Priapism.  Journal of Sexual Medicine 3:1077-1084, 2006.


  80. T.J. Bivalacqua, W. Deng, M. Kendirci, M.F. Usta, C. Robinson, B.K. Taylor, S.N. Murthy, H.C. Champion, W.J.G. Hellstrom, and P.J Kadowitz.  Mesenchymal Stem Cells Alone or Ex Vivo Gene-Modified with Endothelial Nitric Oxide Synthase Reverse Age-Associated Erectile Dysfunction.  American Journal of Physiology: Heart and Circulatory Physiology 292:H1278-1290, 2007.


  81. T.J. Bivalacqua, A.L. Burnett, W.J.G. Hellstrom, and H.C. Champion.  Overexpression of Arginase in the Aged Mouse Penis Impairs Erectile Function and Decreases NOS3 Activity: Influence of In Vivo Gene Therapy of Anti-Arginase.  American Journal of Physiology: Heart and Circulatory Physiology 292:H1340-1351, 2007.


  82. L.L. Hsu, H.C. Champion, S.A. Campbell-Lee, T.J. Bivalacqua, E.A. Manci, B.A. Diwan, D.M. Schimel, A.E. Cochard, X. Wang, A.N. Schechter, C.T. Noguchi, and M.T. Gladwin.  Hemolysis In Sickle Cell Mice Causes Pulmonary Hypertension Due To Global Impairment In Nitric Oxide Bioavailability.  Blood 109:3088-3098, 2007.


  83. T.J. Bivalacqua, H.C. Champion, T. Liu, and A.L. Burnett.  Endothelial Nitric Oxide Synthase Keeps Erection Regulatory Function Balance in the Penis.  European Urology 51:1732-1740, 2007.


  84. T.J. Bivalacqua, M. Kendirci, H.C. Champion, W.J.G. Hellstrom, K.E. Andersson, and P. Hedlund.  Dysregulation of cGMP-Dependent Protein Kinase (PKG) Impairs Erectile Function in Diabetes: Influence of In Vivo Gene Therapy of PKG1a.  BJU International 99:1488-1494, 2007.


  85. B.D. Nossaman, T.J. Bivalacqua, H.C. Champion, S.R. Baber and P.J. Kadowitz.  Analysis of Vasodilator Responses to Peroxynitrite in the Hindlimb Vascular Bed of the Cat.  Journal of Cardiovascular Pharmacology 50:358-366, 2007.


  86. T.J. Bivalacqua, E.M. Schaeffer, L. Mettee, A. Wagner, L.M. Su, and C.P. Pavlovich.  Intraperitoneal Effects of Extraperitoneal Laparoscopic Radical Prostatectomy.  Urology 72:273-277, 2008.


  87. T.J. Bivalacqua, T.J. Guzzo, E.M. Schaeffer, M.A. Gebska, H.C. Champion, A.L. Burnett, and M.L. Gonzalgo.  Application of Evicel to Cavernous Nerves of the Rat Does Not Influence Erectile Function In Vivo.  Urology 72:1169-1173, 2008.


  88. T.J. Guzzo, C.G. Rogers, C.Y. Deng, T.J. Bivalacqua, G.S. Palapattu, P.J. Bastian, M.A. Eisenberger, M.P. Schoenberg and M.L. Gonzalgo.  Outcomes of Patients After Aborted Radical Cystectomy for Intraoperative Findings of Metastatic Disease.  BJU International 102:1539-1543, 2008.


  89. A.L. Burnett, M.E. Allaf, and T.J. Bivalacqua.  Erythropoietin Promotes Erection Recovery after Nerve Sparing Radical Retropubic Prostatectomy: A Retrospective Analysis.  Journal of Sexual Medicine 5:2392-2398, 2008.


  90. A.L. Burnett, T.D. Strong, B.J. Trock, L. Jin, T.J. Bivalacqua, and B. Musicki.  Serum Biomarker Measurements of Endothelial Function and Oxidative Stress after Daily Dosing of Sildenafil in Type 2 Diabetic Men with Erectile Dysfunction.  Journal of Urology 181:245-251, 2009.


  91.  T.J. Bivalacqua, T.E. Sussan, T.D. Strong, D.E. Berkowitz, S.S. Biswal, A.L. Burnett, and H.C. Champion.  Sildenafil Inhibits Superoxide Formation And Prevents Endothelial Dysfunction In A Mouse Model Of Second-Hand Cigarette Smoke Induced Erectile Dysfunction.  Journal of Urology 181:899-906, 2009.


  92. B. Musicki, A.E. Ross, H.C. Champion, A.L. Burnett, and T.J. Bivalacqua.  Post-Translation Modification of Constitutive Nitric Oxide Synthase in the Penis.  Journal of Andrology 30:352-362, 2009. 


  93.  T.J. Bivalacqua, B. Musicki, L.L. Hsu, M.T. Gladwin, A.L. Burnett, and H.C. Champion.  Establishment of a Transgenic Sickle Cell Mouse Model to Study the Pathophysiology of Priapism.  Journal of Sexual Medicine 6:2494-2504, 2009.


  94. T.J. Guzzo, T.J. Bivalacqua, P.M. Pierorazio, E.M. Schaeffer, D.Y. Chan, and M.E. Allaf.  Xanthogranulomatous Pyelonephritis: Presentation and Management in the Laparoscopic Era.  BJU International 104:1265-1268, 2009.


  95. T.J. Guzzo, T.J. Bivalacqua, A. Magheli, M.E. Nielsen, F.J. Attenello, M.P. Schoenberg, and M.L. Gonzalgo.  Pathologic Upstaging at the Time of Radical Cystectomy is Associated with Worse Recurrence Free Survival in Patients with BCG Refractory Bladder Cancer. Urology 74:1276-1280, 2009. 


  96. J.H. Kim, L. Bugaj, T.J. Bivalacqua, S. Ryoo, Y.J. Oh, A. Camara, G. Sikka, D. Nyhan, A. Shoukas, H. C. Champion, and D.E. Berkowitz.  Arginase Inhibition Restores NOS Coupling and Reverses Endothelial Dysfunction and Vascular Stiffness in Old Rats.  Journal of Applied Physiology 107:1249-1257, 2009.


  97. T.J. Guzzo, B.K. McNeil, T.J. Bivalacqua, L.J. Sokoll and M.P. Schoenberg.  Circulating Tumor Cells do not Predict Extravesical Disease in Bladder Cancer Patients Prior to Radical Cystectomy.  Urologic Oncology (in press), 2009.


  98. Musicki B, Liu T, Strong TD, Lagoda GA, Bivalacqua TJ, Burnett AL.  Post-translational Regulation of Endothelial Nitric Oxide Synthase (eNOS) by Estrogens in the Rat Vagina. Journal of Sexual Medicine 7:1768-1777, 2010.


  99. Broderick GA, Kadioglu A, Bivalacqua TJ, Ghanem H, Nehra A, Shamloul R.  Priapism: pathogenesis, epidemiology, and management. Journal of Sexual Medicine. 7: 476-500, 2010.


  100. Deng W, Bivalacqua TJ, Champion HC, Hellstrom WJ, Murthy SN, Kadowitz PJ. Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the lung for pulmonary hypertension. Methods Mol Biol. 610:309-321, 2010.


  101. Deng W, Bivalacqua TJ, Champion HC, Hellstrom WJ, Murthy SN, Kadowitz PJ.  Superoxide dismutase - a target for gene therapeutic approach to reduce oxidative stress in erectile dysfunction. Methods Mol Biol. 610: 213-227, 2010.


  102.  Bivalacqua TJ, Ross AE, Strong TD, Gebska MA, Musicki B, Champion HC, Burnett AL.  Attenuated RhoA/Rho-Kinase Signaling in the Penis of Transgenic Sickle Cell Mice.  Urology 76:510-516, 2010.


  103. Gratzke C, Strong TD, Gebska MA, Champion HC, Stief CG, Burnett AL, Bivalacqua TJ.  Activated RhoA/Rho-kinase Impairs Erectile function after Cavernous Nerve Injury in Rats.  Journal of Urology 184: 2197-2204, 2010.


  104.  Pierorazio PM, Guzzo TJ, Han M, Bivalacqua TJ, Epstein JI, Schaeffer EM, Schoenberg M, Walsh PC, Partin AW.  Long term survival after radical prostatectomy for men with high gleason sum in pathologic specimen.  Urology 76:715-721, 2010. 


  105.  Han M, Trock BJ, Partin AW, Humphreys EB, Bivalacqua TJ, Guzzo TJ, Walsh PC.  The impact of preoperative erectile dysfunction on survival after radical prostatectomy. BJU International 106:1612-1617, 2010.


  106.  Cervellione RM, Husmann DA, Bivalacqua TJ, Sponseller PD, Gearhart JP. Penile ischemic injury in the exstrophy/epispadias spectrum: New insights and possible mechanisms. Journal of Pediatric Urology 6:450-456, 2010 


  107. Bivalacqua TJ, Loeb S, Pierorazio PM, Schoenberg MP, Partin AW, Guzzo TJ.  Is Prostate Specific Antigen Surveillance Necessary in Men with Benign Prostate Pathology Following Radical Cystoprostatectomy for Bladder Cancer.  Urologia Internationalis 85:466-469, 2010.


  108.   Musicki B, Champion HC, Hsu LL, Bivalacqua TJ, Burnett AL.  Post-translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis.  Journal of Sexual Medicine 8:419-426, 2011.


  109.  Johnson JM, Bivalacqua TJ, Lagoda GA, Burnett AL, Musicki B.  eNOS-uncoupling in age-related erectile dysfunction.  International Journal of Impotence Research 23:43-49, 2011.


  110. Musicki B, Champion HC, Hsu LL, Bivalacqua TJ, Burnett AL.  Post-translational inactivation of endothelial nitric oxide synthase in transgenic sickle cell mouse penis.  Journal of Sexual Medicine 8:419-426, 2011.


  111.  Gebska MA, Stevenson BK, Hemnes AR, Bivalacqua TJ, Haile A, Hesketh CG, Murray CL, Zaiman AL, Halushka MK, Krongkaew N, Strong TD, Cooke CA, El-Haddad H, Tuder RM, Berkowitz DE, Champion HC.  Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity.  Cardiovascular Pharmacology 90:353-363, 2011.


  112.  Burnett AL, Bivalacqua TJ.  Priapism: new concepts in medical and surgical management.  Urologic Clinics of North America 38:185-194, 2011.


  113.  Gupta AD, Bandari J, Ross AE, McCall CM, Tufaro A, Bivalacqua TJ.  Management of Primary Squamous Cell Carcinoma at the Mucocutaneous Junction of an Ileal Conduit.  Urology 78:1229-31, 2011.


  114. Guzzo TJ, Hockenberry MS, Mucksavage P, Bivalacqua TJ, Schoenberg MP.  Smoking knowledge assessment and cessation trends in patients with bladder cancer presenting to a tertiary referral center.  Urology 79:166-171, 2012. 


  115. Kutlu O, Ross AE, Schaeffer EM, Gratzke C, Stief CG, Strong TD, Burnett AL, Hedlund P, Bivalacqua TJ.  Increased expression of Nestin, a neural stem cell marker, in the major pelvic ganglion following cavernous nerve injury.  International Journal of Impotence Research 24:84-90, 2012.


  116. Mullins JM, Guzzo TJ, Pierorazio PM, Eifler J, Ball M, Schoenberg MP, Bivalacqua TJ. Stented versus Nonstented Ureteroenteric Anastomosis of Continent and Non-Continent Urinary Diversion after Cystectomy: Effect on Post-operative Morbidity and Stricture Rate.  Urologia Internationalis 88:66-70, 2011.


  117.  Kavalukas SL, Uzgare AR, Bivalacqua TJ, Barbul A.  Arginase inhibition promotes wound healing in mice.  Surgery 151:287-295, 2012.


  118. Guzzo TJ, Resnick MJ, Canter DJ, Bivalacqua TJ, Rosen MA, Bergey MR, Magerfleisch L, Tomazewski JE, Wein AJ, Malkowicz SB. Endorectal T2-weighted MRI does not differentiate between favorable and adverse pathologic features in men with prostate cancer who would qualify for active surveillance.  Urologic Oncology 30:301-5, 2012.


  119. Calenda G, Strong TD, Pavlovich CP, Schaeffer EM, Burnett AL, Yu W, Davies KP, Bivalacqua TJ.  Whole genome microarray of the major pelvic ganglion after cavernous nerve injury: new insights into molecular profile changes after nerve injury.  BJU International 109:1552-64, 2012.


  120. Gur S, Kadowitz PJ, Sikka SC, Bivalacqua TJ, Hellstrom WJ.  Inhibition of sympathetic neuroeffector transmission in human corpus cavernosum.  BJU International 110:856-62, 2012.


  121. Segal R, Hannan JL, Liu X, Kutlu O, Burnett AL, Champion HC, Kim JH, Steppan J, Berkowitz DE, Bivalacqua TJ.  Chronic Oral Administration of the Arginase Inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) Improves Erectile Function in Aged Rats.  Journal of Andrology 33:1169-1175, 2012.


  122. Segal R, Bivalacqua TJ, Burnett AL.  Losartan to preserve erectile function following radical prostatectomy: a retrospective analysis.  BJU International 110:1782-1786, 2012.


  123. Castiglione F, Bergamini A, Bettiga A, Bivalacqua TJ, Benigni F, Strittmatter F, Gandaglia G, Rigatti P, Montorsi F, Hedlund P.  Perioperative betamethasone treatment reduces signs of bladder dysfunction in a rat model for neuropraxia in female urogenital surgery.  European Urology 62:1076-85, 2012.


  124. Pierorazio PM, Mullins JK, Eifler JB, Voth K, Hyams ES, Han M, Pavlovich CP, Partin AP, Bivalacqua TJ, Allaf ME, Schaeffer EM.  Contemporaneous comparison of open versus minimally-invasive radical prostatectomy for high risk prostate cancer.  BJU International (in press), 2012. 


  125.  Pierorazio PM, Mullins JK, Hyams ES, Partin AW, Han M, Walsh PC, Schaeffer EM, Pavlovich CP, Allaf ME, Bivalacqua TJ.  Trends in Immediate Perioperative Morbidity and Delay in Discharge Following Radical Prostatectomy: A 20-year Institutional Experience.  BJU International (in press), 2012.


  126. Segal R, Readal N, Pierorazio PM, Burnett AL, Bivalacqua TJ.  Corporal "Snake" Maneuver for the Treatment of Ischemic Priapism: Long Term Followup.  Journal of Urology (in press), 2012.


  127. Mulhall JP, Bivalacqua TJ, Becher E.  Standard Operating Procedures for the Preservation of Erectile Function Outcomes after radical prostatectomy.  Journal of Sexual Medicine (in press), 2012.


  128. Bivalacqua TJ, Musicki B, Hu L, Gladwin M, Champion HC, Burnett AL.  PDE5 Dysregulation and Nitric oxide Imbalance in Sickle Cell Disease Associated Priapism.  Proceeding of the National Academy of Sciences (submitted), 2012.


  129. Hannan JL, Albersen M, Kutlu O, Gratzke C, Stief CG, Burnett AL, Lysiak JJ, Hedlund P, Bivalacqua TJ. Inhibition of Rho-kinase Improves Erectile Function, Increases Nitric Oxide Signaling and Decreases Penile Apoptosis in a Rat Model of Cavernous Nerve Injury. Journal of Urology (in press), 2012.


  130. Castiglione F, Hedlund P, Van der Aa F, Bivalacqua TJ, Rigatti P, Van Poppel H, Montorsi F, De Ridder D, Albersen M. Intratunical Injection of Human Adipose Tissue-derived Stem Cells Prevents Fibrosis and Is Associated with Improved Erectile Function in a Rat Model of Peyronie's Disease. European Urology (in press) 2012.


  131. Rubio-Aurioles E, Bivalacqua TJ. Standard Operational Procedures for Low Sexual Desire in Men. Journal of Sexual Medicine (in press), 2012.


  132. Cellek S, Bivalacqua TJ, Burnett AL, Chitaley K, Lin CS. Common Pitfalls in Some of the Experimental Studies in Erectile Function and Dysfunction: A Consensus Article. Journal of Sexual Medicine 9:2770-84, 2012.


  133. Segal RL, Readal N, Pieororazio PM, Kutlu O, Schoenberg M, Bivalacqua TJ.  Radical Cystectomy in Patients with Preexisting Three-Piece Inflatable Penile Prosthesis.  Journal of Sexual Medicine (in press), 2012.


  134. Massanyi EZ, Gupta A, Goel S, Gearhart JP, Burnett AL, Bivalacqua TJ, Redett RJ.  Radial Forearm Free Flap Phalloplasty for Penile Inadequacy in Exstrophy Patients. Journal of Urology (in press), 2012.


  135. Pierorazio PM, Gorin MA, Ross AE, Feng Z, Trock BJ, Schaeffer EM, Han M, Epstein JI, Partin AW, Walsh PC, Bivalacqua TJ.  Pathological and Oncologic Outcomes for Men with Positive Lymph Nodes at Radical Prostatectomy: The Johns Hopkins Hospital 30-year Experience.  Urologic Oncology (submitted), 2012.


  136. Bivalacqua TJ, Pierorazio PM, Ross AE, Allaf ME, Carter BE, Walsh PC.  Anatomical Extent of Lymph Node Dissection:  Impact on Men with Positive Lymph Nodes at Time of Radical Prostatectomy.  Urology (submitted), 2012.  


  137. Kaye DR, Hyndman E, Segal RL, Mettee LZ, Trock BJ, Feng Z, Su LM, Bivalacqua TJ, Pavlovich CP.  Urinary outcomes are significantly affected by nerve-sparing quality during radical prostatectomy. Journal of Urology (submitted), 2012.


  138. Gorin MA, Kates M, Mullins JK, Pierorazio PM, Schoenberg MP, Bivalacqua TJ.  Impact of Hospital Volume on Perioperative Outcomes and Costs of Radical Cystectomy: Analysis of the Maryland Health Services Cost Review Commission Database.  Urology (submitted), 2013.


  139. Jayram G, Allaf ME, Netto G, Schoenberg MP, Bivalacqua TJ. ConcomitantLaparoscopic Nephroureterectomy and Open Cystectomy for Upper and Lower Tract Urothelial Carcinoma. Journal of Endourology (submitted), 2013. 



EDUCATIONAL ACTIVITIES

Educational Publications
Review Articles

  1. W.J.G. Hellstrom and T.J. Bivalacqua.  Peyronie’s Disease:  Etiology, Medical, and Surgical Therapy.  Journal of Andrology 21:347-354, 2000. 

  2. T.J. Bivalacqua, H.C. Champion, W.J.G. Hellstrom, and P.J. Kadowitz.  Pharmacotherapy for Erectile Dysfunction.  Trends in Pharmacological Sciences 21:484-489, 2000.

  3. T.J. Bivalacqua, S.K. Purohit, and W.J.G. Hellstrom.  Peyronie’s Disease:  Advances in Basic Science and Pathophysiology.  Current Urology Reports 1:297-301, 2000.

  4. T.J. Bivalacqua and W.J.G. Hellstrom.  Potential Application of Gene Therapy in the Treatment of Erectile Dysfunction.  Journal of Andrology 22:183-190, 2001.

  5. T.J. Bivalacqua, H.C. Champion, and W.J.G. Hellstrom.  Implications of Nitric Oxide Synthase Isoforms in the Pathophysiology of Peyronie’s Disease.  International Journal of Impotence Research 14:345-352, 2002.

  6. T.J. Bivalacqua, H.C. Champion, M.F. Usta, P.J. Kadowitz, and W.J.G. Hellstrom.  Endothelial Dysfunction in Erectile Dysfunction: Role of the Endothelium in Erectile Physiology and Disease.  Journal of Andrology 24:S17-S37, 2003.

  7. M. Kendirci, T.J. Bivalacqua, and W.J.G. Hellstrom.  Vardenafil: A Novel Type 5 Phosphodiesterase Inhibitor for the Treatment of Erectile Dysfunction.  Expert Opinion in Pharmacotherapy 5:923-932, 2004. 

  8. B.A. Bunnell, W. Deng, C.M. Robinson, P.R. Waldron, T.J. Bivalacqua, S.R. Baber, P.J. Kadowitz. Potential Application of Mesenchymal Stem Cells for Treatment of Cardiovascular Diseases. Canadian Journal of Physiology and Pharmacology 83:529-539, 2005.

  9. T.J. Bivalacqua, B. Musicki, M.F. Usta, H.C. Champion, P.J. Kadowitz, A.L. Burnett, W.J.G. Hellstrom.  Endothelial Nitric Oxide Synthase Gene Therapy for Erectile Dysfunction.  Current Pharmaceutical Design 11:4059-4067, 2005. 

  10. W. Deng, T.J. Bivalacqua, W.J.G. Hellstrom, and P.J. Kadowitz.  Gene and Stem Cell Therapy for Erectile Dysfunction.  International Journal of Impotence Research 17:S57-S63, 2005

  11. A.L. Burnett, B. Musicki, L. Jin, and T.J. Bivalacqua. Nitric Oxide/Redox-Based Signaling a Therapeutic Target for Penile Disorders.  Expert Opinion in Therapeutic Targets 10:445-457, 2006.

  12. T.J. Bivalacqua and A.L. Burnett. Priapism:  New Concepts in the Pathophysiology and New Treatment Strategies.  Current Urology Reports 7:497-502, 2006.

  13. M. Kendirci, P.C. Teloken, H.C. Champion, W.J.G. Hellstrom, and T.J. Bivalacqua.  Gene Therapy for Erectile Dysfunction:  Fact or Fiction?  European Urology 50:1208-1222, 2006. 

  14. A.L. Burnett and T.J. Bivalacqua.  Priapism: Current Principles and Practice.  Urologic Clinics of North America 34:631-642, 2007.

  15. T.D. Strong, M.A. Gebska, A.L. Burnett, H.C. Champion, and T.J. Bivalacqua.  Endothelium-specific gene and stem cell-based therapy for erectile dysfunction.  Asian Journal of Andrology 10:14-22, 2008.

  16. T.J. Bivalacqua and T.D. Strong.  The Use of Gene Transfer Technology to Study the Pathophysiology of Erectile Dysfunction.  Journal of Sexual Medicine 5:268-275, 2008.

  17. T. D. Strong, H.C. Champion, A.L. Burnett and T.J. Bivalacqua.  Stem and Endothelial Progenitor Cells in Erectile Biology.  Internal Journal of Impotence Research 20:243-254, 2008.

  18. T.J. Guzzo, T.J. Bivalacqua, and M.P. Schoenberg.  Bladder Cancer and the Aluminum Industry:  A Review of the Literature.  BJU International 102:1058-1060, 2008.

  19. B. Musicki B, T. Liu, G.A. Lagoda, T.J. Bivalacqua, T.D. Strong, and A.L. Burnett.  Endothelial Nitric Oxide Synthase Regulation in Female Genital Tract Structures.  Journal of Sexual Medicine 6:247-253, 2009.

  20. T.J. Bivalacqua, P.M. Pierorazio, and L.M. Su. Open, Laparoscopic, and Robotic Radical Prostatectomy: Optimizing the Surgical Approach.  Surgical Oncology 18:233-241, 2009.

  21. Levey HR, Kutlu O, Bivalacqua TJ.  Medical Management of Ischemic Stuttering Priapism: A contemporary review of the literature.  Asian Journal of Andrology 14:156-163, 2012.

  22. Bivalacqua TJ, Musicki B, Kutlu O, Burnett AL.  New insights into the pathophysiology of sickle cell disease-associated priapism. Journal of Sexual Medicine 9:79-87, 2012.

  23. Bivalacqua TJ.  Metabolomics and Urologic Oncology.  Urologic Oncology 29:550, 2011.

  24. Hyndman ME, Mullins J, Bivalacqua TJ.  Metabolomics and Bladder Cancer.  Urologic Oncology 29:558-561, 2011.

  25. Hyndman ME, Kaye D, Field NC, Lawson KA, Smith ND, Steinberg GD, Schoenberg MP, Bivalacqua TJ. The use of regenerative medicine in the management of invasive bladder cancer. Advances in Urology (in press). 2012.

  26. Hakim L, Van der Aa F, Bivalacqua TJ, Hedlund P, Albersen M. Emerging tools for erectile dysfunction: a role for regenerative medicine. Nature Reviews in Urology 9:520-536, 2012.

Editorials

  1. M.F. Usta, T.J. Bivalacqua, and W.J.G. Hellstrom.  Re: optimizing treatment for diabetes mellitus induced erectile dysfunction.  Journal of Urology 171:1638-1639, 2004. 

  2. T.D. Strong, H.C. Champion, P.J. Kadowitz, and T.J. Bivalacqua.  Re: Potential Differentiation of Human Mesenchymal Stem Cell Transplanted In Rat Corpus Cavernosum Toward Endothelial Or Smooth Muscle Cells.  International Journal of Impotence Research 19:530, 2007.

  3. Chow NH, Knowles M, Bivalacqua TJ. Urothelial carcinoma. Advances in Urology (in press), 2012.



Case Reports

  1. T.J. Bivalacqua, H. Alphs, E.M. Schaeffer, and M.P. Schoenberg.  Paraneoplastic Polyarthritis from Non-Small Cell Lung Cancer Metastatic to the Bladder.  Journal of Clinical Oncology 25:2621-2623, 2007.

  2. H.H. Alphs, J. Miles-Thomas, F. Attenollo, J.M. Taube, G. Fonseca, M.P. Schoenberg, and T.J. Bivalacqua.  Presentation and management of a patient with subcutaneous metastatic transitional cell carcinoma of the bladder.  Nature Clinical Practice Urology 5:691-694, 2008.

  3. A.L. Burnett and T.J. Bivalacqua.  Glucose-6-Phosphate Dehydrogenase Deficiency: An Etiology for Idiopathic Priapism?  Journal of Sexual Medicine 5:237-240, 2008.

  4. E.M. Schaeffer, T.J. Bivalacqua, S. Hortopan, C. Weiss, S. Mitchell, and M.E. Allaf.  Cystoscopic Management of an Extruded Coil from Arteriovenous Fistula Embolization Using Arthroscopic Instruments.  Journal of Endourology 22:1527-1529, 2008.

  5. T.J. Bivalacqua, H.S. Bagga, K. Patil, A. Magheli, J. Taube, T.J. Guzzo, and M.L. Gonzalgo.  Carcinosarcoma of the Urethra from a Primary Bladder Carcinosarcomatous Lesion:  Analysis of Clinicopathologic Features.  Canadian Journal of Urology 16:4345-4348, 2009.

  6. Pierorazio PM, Bivalacqua TJ, Burnett AL.  Daily phosphodiesterase type 5 inhibitor therapy as rescue for recurrent ischemic priapism after failed androgen ablation: A case report.  Journal of Andrology 32:371-374, 2011.



  7. Reese AC, Ball MW, Efron JE, Chang A, Meyer C, Bivalacqua TJ.  Favorable Response to Neoadjuvant Chemotherapy and Radiation in Patient with Prostatic Stromal Sarcoma.  Journal of Clinical Oncology 30:353-355, 2012. 



Book Chapters

  1. W.J.G. Hellstrom, T.J. Bivalacqua, P.J. Kadowitz and P.C. Doherty.  Type 3, 4 and 5 Phosphodiesterase Inhibitors Influence Penile Erection in the Cat.  In: 8th World Meeting  on  Impotence Research, Meuleman, E., Nijehot, G.L., and Vanderschueren, D. (eds.), pgs. 219-224, 1998. 

  2. T.J. Bivalacqua, H.C. Champion, P.J. Kadowitz, P.C. Doherty and W.J.G. Hellstrom.  Potentiation of Erectile Response by Combination of Prostaglandin E1 and Rolipram in the Cat. In: 8th World Meeting on Impotence Research.  Meuleman, E., Nijehot, G.L.,   and Vanderschueren, D. (eds.), pgs. 225-229, 1998. 

  3. H.C. Champion, D.G. Lambert, T.J. Bivalacqua, D.B. McNamara, and P.J. Kadowitz.  Comparison of the Inhibitory Actions of Angiotensin AT1 Receptor Antagonists in the Peripheral Vascular Bed.  In: Angiotensin II Receptor Blockade Physiological and Clinical Implications, Dhalla N.S., Zahradka P., Dixon I.M.C., Beamish R.E. (eds.), pgs. 65-86, 1998.   

  4. T.J. Bivalacqua, H.C. Champion, P.J. Kadowitz, and W.J.G. Hellstrom.  Nitric Oxide Effect on Penile Blood Flow and Lower Genitourinary Tract Function.  In:  Nitric Oxide and the Regulation of the Peripheral Circulation.  Kadowitz, P.J. and McNamara, D.B. (eds.), New York: Springer-Verlag NY, Inc., pgs. 286-301, 2000. 

  5. P.J. Kadowitz, A.L. Hyman, B.D. Nossaman, T. J. Bivalacqua, W.A. Murphy, D.H. Coy, D.B. McNamara, and H.C. Champion.  Cadiovascular Actions of Adrenomedullin.  In:  The CGRP Family: Calcitonin Gene-Related Peptide, Amylin, and Adrenomedullin.  Poyner D., Marshall, I, and Brain, S. (eds), Georgetown: Landes Biosecience, pgs. 115-122, 2000. 

  6. H.C. Champion, R.L. Pierce, T.J. Bivalacqua, W.A. Murphy, D.H. Coy, and P.J. Kadowitz. Analysis of Responses to hAmylin and hCGRP in Isolated Resistance Arteries from the Mesenteric Vascular Bed of the Rat.  In:  The CGRP Family: Calcitonin Gene-Related Peptide, Amylin, and Adrenomedullin.  Poyner D., Marshall, I, and Brain, S. (eds), Georgetown: Landes Biosecience, pgs. 189-190, 2000.

  7. H.C. Champion, T.J. Bivalacqua, R. Wang, W.J.G. Hellstrom, W.A. Murphy, D.H. Coy, and P.J. Kadowitz.  Effects of ADM and CGRP on Erectile Activity in the Cat.  In:  The CGRP Family: Calcitonin Gene-Related Peptide, Amylin, and Adrenomedullin.  Poyner D., Marshall, I, and Brain, S. (eds), Georgetown: Landes Biosecience, pgs. 199-201, 2000. 

  8. T.E. Novak, T.J. Bivalacqua, R. Davis, and W.J.G. Hellstrom.  Management of Erectile Dysfunction following Radical Prostatectomy.  In: Male Sexual Function: A Guide to   Clinical Management.  J.J. Mulcahy (ed), The Humana Press, Inc. pgs. 109-122, 2001.  

  9. T.J. Bivalacqua, M.F. Usta, and R. Wang.  Animal models for the study of erectile dysfunction. In: Sexual Dysfunctions. C. Teloken, C. Teodosio Da Ros, M. Tannhauser (eds), Brazile publisher, pgs. 34-38, 2004.

     
  10. M.F. Usta, T.J. Bivalacqua, and W.J.G. Hellstrom.  Peyronie’s Disease.  In: Sexual Dysfunctions. C. Teloken, C. Teodosio Da Ros, M. Tannhauser (eds), Brazile publisher, pgs. 214-221, 2004. 

  11. K. McKenna, T.J. Bivalacqua, M. Baum, L. Coolen, P. Hedlund, K. Park, E. Pescatori, J. Rajfer, and Y. Sato.  Experimental Studies of Sexual Functions and Dysfunctions Including Brain Imaging Studies.  In: Erectile Dysfunction T.F. Lue, R. Basson, F. Giuliano, F. Montorsi, R. Rosen (eds), World Health Organization, Paris, France, 2004.

  12.   T.J. Bivalacqua and M. Allaf.  Erectile Dysfunction and Peyronie’s Disease.  In: The Brady Urology Manual, J.K. Parsons, E.J. Wright (eds), pgs. 51-62, 2006.

  13. M. Allaf and T.J. Bivalacqua.  Priapism.  In: The Brady Urology Manual, J.K. Parsons, E.J. Wright (eds), pgs. 273-278, 2006.

  14. T.J. Bivalacqua, T.D. Strong, H.C. Champion, and A.L. Burnett.  Stem and Endothelial Progenitor Cells in Erectile Biology:  Future Therapeutic Applications and Potential Biomarker for ED.  In: Textbook of Erectile Dysfunction, 2nd Edition; Carson, Kirby, Goldstein, Wyllie (eds), (in press), 2009.

  15. T.J. Bivalacqua, B. Musicki, H.C. Champion, and A.L. Burnett.  Phosphodiesterase Type 5 Inhibitor Therapy for Priapism.  In: Textbook of Erectile Dysfunction, 2nd Edition; Carson, Kirby, Goldstein, Wyllie (eds), (in press), 2009.

  16.   T.J. Bivalacqua, and A.L. Burnett.  Operations for Priapism.  In:  Hinman’s Atlas of Urologic Surgery, 3rd Edition; Resnick, McGuire, Howards, Preminger, Smith (eds), (in press), 2009.

  17. T.J. Bivalacqua, and A.L. Burnett.  Priapism.  In: Glenn’s Urologic Surgery, 7th Edition; Graham and Keane (eds), pgs 487-492, 2010.A. Schaeffer, and T.J. Bivalacqua.  Erectile Dysfunction.  In: 5 Minute Urology Consult;  Gomella (ed),  pgs 118-119, 2010.



  18.   A. Schaeffer, and T.J. Bivalacqua.  Peyronie’s Disease.  In: 5 Minute Urology Consult; Gomella (ed), pgs 256-257, 2010.



  19.   A. Schaeffer, and T.J. Bivalacqua.  Urinary Tract Infection in Men.  In: 5 Minute Urology Consult;  Gomella (ed), pgs 508-509, 2010.



  20.   T. Lally, Burnett AL, and T.J. Bivalacqua.  Scleroderma and Erectile Dysfunction.  In: Scleroderma: From Pathogenesis to Comprehensive Management; Varga, Denton, Wigley (eds) (in press), 2012.

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