| My research applies molecular biology to develop and screen highly
diverse polymer libraries with the goal of developing new diagnostic,
prognostic, and therapeutic agents for urologic oncology,
particularly prostate cancer. We have used these techniques to
develop RNA aptamers, peptides, and adenoviral gene therapy vectors
to prostate cancer cell surface antigens. These agents are being
used to target viruses, nanoparticles, imaging agents, and siRNA to
prostate cancer cells expressing PSMA. My research interests also
include urologic tissue specificity, for example, determining what
qualities are specific to prostate cells and how can these be applied
to generate new experimental diagnostic and therapeutic agents for
prostate cancer.
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