November 22, 2009


Shawn E Lupold, Ph.D.

Assistant Professor
The James Buchanan Brady Urologic Institute

Director, Small Animal Imaging Resources Program Molecular Biology Core
Johns Hopkins University School of Medicine


Email:slupold1@jhmi.edu

My research applies molecular biology to develop and screen highly diverse polymer libraries with the goal of developing new diagnostic, prognostic, and therapeutic agents for urologic oncology, particularly prostate cancer. We have used these techniques to develop RNA aptamers, peptides, and adenoviral gene therapy vectors to prostate cancer cell surface antigens. These agents are being used to target viruses, nanoparticles, imaging agents, and siRNA to prostate cancer cells expressing PSMA. My research interests also include urologic tissue specificity, for example, determining what qualities are specific to prostate cells and how can these be applied to generate new experimental diagnostic and therapeutic agents for prostate cancer.

 
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