July 24, 2008


Ronald Rodriguez, M.D., Ph.D.

Associate Professor of Urology, Medical Oncology, Cellular & Molecular Medicine
Residency Program Director
Johns Hopkins Medical Institutions

Email:rrodriguez@jhmi.edu

    Free Access to abstracts at PubMed
Peer Reviewed Articles

PEER-REVIEWED SCIENTIFIC ARTICLES

  1. Heath EI, DeWeese TL, Partin AW, DeMarzo AM, Groopman JD, Nelson WG, Rodriguez, R., Piantadosi SA, Carter HB, Schoenberg MP, Yang VW, Hubbard WC, Dannenberg AJ, Lieberman R, Walczak J, Gurganus R, Stewart J, Carducci MA. The design of a randomized, placebo-controlled trial of celecoxib in pre-prostatatectomy men with clinically localized adenocarcinoma of the prostate. Clinical Prostate Cancer 1:182-187, 2002.
  2. Van Der PoelL HG, Molenaar B, Van Beusechem VW, Haisma HJ, Rodriguez, R., Curiel DT, Gerritsen WR. Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer. J Urol 2002 Jul;168(1):266-72.
  3. Sachs, M, Rauen, KA, Ramamurthy, M, Dodson, J, De Marzo AM, Putzi, MJ, Schoenberg, MP, Rodriguez, R. Integrin Alphav and Coxsackie-Adenovirus Receptor (CAR) in Clinical Bladder Cancer, Urology, Urology, 60(3):165-170.
  4. Li, Y, McCadden, J, Ferrer, F, Kruszewski, M, Carducci, M, Simons, J, Rodriguez, R. Prostate Specific Expression of the Diphtheria Toxin A Chain(DT-A): Studies of Inducibility and Specificity of Expression of PSA Promoter-Driven DT-A Adenoviral Gene Transfer. Cancer Research, 62(9):2576-82, 2002.
  5. van Der Poel, H. G., McCadden, J., Verhaegh, G. W., Kruszewski, M., Ferrer, F., Schalken, J. A., Carducci, M., Rodriguez, R. A novel method for the determination of basal gene expression of tissue- specific promoters: An analysis of prostate-specific promoters. Cancer Gene Ther, 2001. 8(12): p. 927-35.
  6. Kirkman, W., 3rd, Chen, P., Schroeder, R., Feneley, M. R., Rodriguez, R., Wickham, T. J., King, C. R., Bruder, J. T.Transduction and apoptosis induction in the rat prostate, using adenovirus vectors. Hum Gene Ther, 2001. 12(12): p. 1499-512.
  7. DeWeese, T. L., van der Poel, H., Li, S., Mikhak, B., Drew, R., Goemann, M., Hamper, U., DeJong, R., Detorie, N., Rodriguez, R., Haulk, T., DeMarzo, A. M., Piantadosi, S., Yu, D. C., Chen, Y., Henderson, D. R., Carducci, M. A., Nelson, W. G., Simons, J. W. A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy. Cancer Res, 2001. 61(20): p. 7464-72.
  8. DeWeese TL, Drew R, Li S, Goemann MA, Mikhak B, Rodriguez, R, Hamper U, DeJong MR, Detorie N, Simons JW. Results of a phase I study of CN706, a replication-competent cytolytic adenovirus, for the treatment of adenocarcinoma of the prostate which is locally-recurrent following radiation therapy. Int J Radiat Oncol Biol Phys 2000; Jan 1;48(3 Suppl 1):172-173.
  9. Karth, J, Ferrer F, Perlman, E, Hanrahan, C, Simons, J, Gearhart, J P, and Rodriguez, R. Co-expression of Hypoxia Inducible Factor-1-Alpha and Vascular Endothelial Growth Factor in Wilms' Tumor. J Pediatr Surg. 2000 Dec;35(12):1749-53.
  10. Han, M., Walsh, P., Partin, A., Rodriguez, R. Ability of the 1992 and 1997 American Joint Committee On Cancer (AJCC) Staging Systems for Prostate Cancer To Predict Progression Free Survival Following Radical Prostatectomy For T2 Disease. J Urol. 2000 Jul;164(1):89-92.
  11. Rodriguez, R., and Walsh, P. C. Trousseau's Syndrome Presenting in a Patient with Metastatic Prostate Cancer, J Urol. 2000 Jun;163(6):1877.
  12. Dyer, B W, Ferrer, F A, Klinedinst, D, and Rodriguez, R. A Non-commercial Dual Luciferase Enzyme Assay System for Reporter Gene Analysis. Anal Biochem. 2000 Jun 15;282(1):158-61
  13. Rodriguez, R, Chan, D., Bishoff, J. T., Chen, R, Kavoussi, L., and Marshall, F.F. Renal Ablative Cryosurgery In Select Patients With Peripheral Renal Masses. Urology 55(1):25-30. Jan 2000.
  14. Silver, R., Rodriguez, R., Han, M., and Gearhart, JP. In vitro fertilization is associated with an increased risk of hypospadias. J. Urol. 161(6):1954-7.1999.
  15. Fradin, J M, Rodriguez, R, Moore, R, Regan. Hydronephrosis in Pregnancy: Simultaneous Depiction of Fetal and Maternal Hydronephrosis by MR Urography, Urology 53(4):825-7, Apr 1999.
  16. Rodriguez, R., Lim, H-Y., Bartkowski, M., and Simons, J. Identification of Diphtheria Toxin as a Potent Cell Cycle Independent Cytotoxin for Human Prostate Cancer Therapeutics. Prostate 34(4):259. 1998.
  17. Dockery W. D., George, D., and Rodriguez, R., Splenosis Presenting as a Mass on Digital Rectal Exam, J Urol, 158(6):2244, Dec 1997.
  18. Rodriguez, R, Schuur, E R., Lim, H Y., Henderson, G A., Simons, J W., Henderson, D. R. Prostate Attenuated Replication Competent Adenovirus CN706: A Selective Cytotoxic for Prostate-specific Antigen-positive Prostate Cancer Cells, Can Res 57:2559-2563, 1997.
  19. Regan, F., Petronis, J., Bohlman, M., Rodriguez, R., and Moore, R. Perirenal MR High Signal- A New and Sensitive Indicator of Acute Ureteric Obstruction, Clinical Radiology 52:445-450, 1997.
  20. Rodriguez, R, and Alfert, H. Endocervicosis: A Rare Mucinous Analog of Endometriosis, J Urol. Journal of Urology. 157(4):1355, 1997 Apr.
  21. Regan, F., Bohlman, ME., Khazan, R., Rodriguez, R., Schultze-Haakh, H . MR urography using HASTE imaging in the assessment of ureteric obstruction. American Journal of Roentgenology. 167(5):1115-20, 1996 Nov.
  22. Ben-Chaim J. Rodriguez, R. Docimo SG. Concealed umbilical stoma: description of a modified technique. J Urol. 154(3):1169-70, 1995 Sep.
  23. Rodriguez, R., Weigel, N. L., O'Malley, B. W., and Schrader, W. T., (1990) Dimerization Of The Chicken Progesterone Receptor In Vitro Can Occur In The Absence of Hormone and DNA, Molecular Endocrinology 4(12), 1782-1790.
  24. Klein-Hitpass, L., Tsai, S. Y., Weigel, N. L., Allan, G. F., Riley, D., Rodriguez, R, Schrader W. T., Tsai, M-J., O'Malley, B. W., (1990) The Progesterone Receptor Stimulates Cell-Free Transcription By Enhancing The Formation Of A Stable Pre-Initiation Complex, Cell 60(2), 247-57.
  25. Rodriguez, R, Carson, M. A., Weigel, N. L., O'Malley, B. W., and Schrader, W. T., (1989) Hormone Induced Changes in the in vitro DNA Binding Activity Of The Chicken Progesterone Receptor, Molecular Endocrinology 3(2), 356-362.
  26. Weaver, J. C., Seissler, P. E., Threefoot, S. A., Lorenz, J. W., Huie, T., R. Rodriguez, and Klibanov, A. M., (1985) Microbiological Measurements By Immobilization Of Cells Within Small-Volume Elements, Enzyme Engineering 7, Vol 434, Annals of the New York Academy of Sciences, 363-372.

Peer Reviewed Articles

INVITED ARTICLES, REVIEWS & CHAPTERS

  1. Chan, D, and Rodriguez, R Renal Cryosurgery. Minimally Invasive Alternatives in Urology, Kaplan, Partin & Atalla eds, in press 2002
  2. Partin, A., Rodriguez, R, and Coffey, DS. The Molecular Biology, Endocrinology And Physiology Of The Prostate And Seminal Vesicles, Campbell’s Urology, 2002.
  3. Ferrer, F and Rodriguez, R Gene Therapy of Prostate Cancer Hematology-Oncology Clinics of North America, 15(3):497-508, 2001.
  4. Rodriguez, R, Jarret, T., Burnett, A. Genitourinary System. Chapter in: Surgery Scientific Priniciples. (ed. K. Lillimoe), 2001
  5. Ferrer, F, Marshall, FF, and Rodriguez, R Urologic Applications of Gene Therapy, AUA Update series, Volume XX, 2001
  6. Gonzalgo, M L, Schoenberg, M P and Rodriguez, R Biological Pathways to Bladder Carcinogenesis. Seminars in Urologic Oncology, 18(4):256-263, 2000.
  7. Chan, DY, Rodriguez, R, Marshall, F F. Renal Ablative Cryosurgery. AUA Update series, Lesson 18, Volume XIX, 2000
  8. Rodriguez, R and Simons, JW. Urologic Applications of Gene Therapy, Urology 54(3):401-6, 1999.
  9. Rodriguez, R and Carter, H B. Current Management of Prostate Cancer, Adv Surg. 1999;33:181-97.
  10. Rodriguez, R. Fishman EK. Marshall FF. Differential diagnosis and evaluation of the incidentally discovered renal mass. Semin Urol Oncol. 13(4):246-53, 1995 Nov.
  11. Weigel, N. L., Rodriguez, R, Carson-Jurica, M. A., Compton, J. G., Birnbaumer, M. E., Schrader, W. T., (1989) Steroid Hormone Receptors: Purification And Characterization, Hormone Action and Molecular Endocrinology, Thirteenth Edition.

Peer Reviewed Articles


SUBMITTED / UNDER REVIEW

  1. Sachs, M., Ramamurthy, M., van der Poel, H., Wickham, T., Lamfers, M., Gerritsen, W., Chowdhury, W., Li, Y., Schoenberg, M., and Rodriguez, R Up-regulation of the Coxsackie-Adenovirus Receptor (CAR) in Bladder Cancer by Histone Deacetylase Inhibitors. Submitted Cancer Research Sept 2002.

Peer Reviewed Articles


MANUSCRIPTS IN PREPARATION

  1. Chowdhury, W. and Rodriguez, R DPL, A Diphtheria Toxin Resistant Adenovirus Packaging Cell Line for Generating Diphtheria Toxin Suicide Gene Therapy Vectors.
  2. Lupold, S. and Rodriguez, R Peptide Ligands directed against the extracellular portion of the Prostate Specific Membrane Antigen.
  3. Li, Y, Yu, D.C. and Rodriguez, R The Adenoviral E1a gene Negatively Regulates Androgen Receptor Function: Implications for Prostate Specific Oncolytic Gene Therapy.
  4. Cohen, M., Drake, C., Neilson, M and Rodriguez, R Immuno-cryotherapy, evaluation of an animal model with possible clinical implications
 
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