Naseruddin   Höti, Ph.D.
Naseruddin Höti, Ph.D.

Instructor
Department of Urology, Johns Hopkins University School of Medicine

Address:
600 N. Wolfe St., Park Building, Room 202C
Baltimore, MD 21287

Email: nhoti1@jhmi.edu

Publications


  1. Naseruddin Höti, Zhu DE, Song Z, Wu Z, Tabassum S, Wu M p53-dependent apoptotic mechanism of a newdesigner bimetallic compound tri-phenyl tin benzimidazolethiol copper chloride (TPT-CuCl2): in vivo studies inWistar rats as well as in vitro studies in human cervical cancer cells. J Pharmacol Exp Ther. (2004) 1:22-33

  2. Song Z, Liu S, He H, Höti N, Wang Y, Feng S, Wu M A single amino acid change (Asp 53 --> Ala53) convertsSurvivin from anti-apoptotic to pro-apoptotic. Mol.Biol.Cell. (2004)1287-96

  3. Naseruddin Höti, Jun Ma, Tabasum S, Yi Wang, and Mian Wu* "Triphenyl tin benzimidazolethiol, a novel antitumor agent induces mitochondrial-mediated apoptosis in human cervical cancer via suppression of HPV-18 encoded E6" Journal of Biochemistry(2003) Oct;4:521-8

  4. B.Ren, N.Höti, X.Rabasseda,Y.Z Wang and M.Wu "The Antiangiogenic and Therapeutic Implication of Endostatin" Journal of Methods Find Exp Clin Pharmocol2003, 25(3):215-224.

  5. De-e Zhu, Naseruddin Höti, Zhiyin Song, Lei Jin, ZhengSheng Wu, Qiang Wu, and Mian Wu,*Suppression of tumor growth using a recombinant Adenoviral vector carrying the dominant negative mutant gene Survivin-D53A in a nude mice model Cancer Gene therapy2006 Aug;13(8):762-70). (Co-First authors)

  6. Xia Q, Chowdhury W  Chen CL, Carducci M, Höti N , Shabbeer S and *Ronald Rodriguez Chronic, But Not Acute, Administration of Valproic Acid Inhibits Prostate Cancer Cell Growth in vitro Cancer Research2006;66(14):7237-44.

  7. Naseruddin Höti, Shawn E. Lupold, Wasim Chowdhury, Ronald Rodriguez* "Valporic acid a Histone Deacetylase Inhibitor Is an Antagonist for Oncolytic Adenoviral Gene Therapy" Molecular Therapy2006 Dec;14(6):768-78.

  8. Naseruddin Höti and Ronald Rodriguez "Gene Therapy for the prostate Cancer" AUANews Nov 2005, page 12. Review article

  9. Naseruddin.Höti Ying Lia, Chien-Lun Chen, David C. Johns, Qinghua Xia ,Arup Kabul , Jer-Tsong Hsieh and Ronald Rodriguez* Androgen Receptor attenuation of Ad5 replication: implications for the development of conditionally replication competent Adenoviruses. Molecular Therapy 2007 Aug;15(8):1495-503

  10. Feng S, Yang Y, Mei Y, Ma L, Zhu DE, Höti N, Castanares M, Wu M*.Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell Signal. 2007 Oct;19(10):2056-67

  11. Siraj Sami, Naseruddin Höti, Han-Mei Xu, Zilong Shen, Xiaofeng Huang Valproic acid inhibits the growth of cervical cancer both in vitro and in vivo. Journal of Biochemistry(2008 Sep;144(3):357-62

  12. Naseruddin Höti, Sadaf Musfata, Wasim Chowdhury, Shawn E. Lupold, Ronald Rodriguez*
    Host Defense Turned Viral Offense, Prostate specific CRAds using RNA interference. (Manuscript in Revision)

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