Demetrios Simopoulos, MD

Assistant Professor of Urology
600 N. Wolfe Street, Marburg 149 Baltimore, MD 21287

Office: 410-614-1729

Fax: 410-955-0833



Education and Training

Education and Training
1991                 B.A., Classical Studies, Pomona College, Claremont, California
1995                 M.D., Tulane University School of Medicine, New Orleans, Louisiana
1995-1996         Internship in General Surgery, Mayo Graduate School of Medicine, Rochester, Minnesota
1996-2001         Residency in Urological Surgery, Mayo Graduate School of Medicine, Rochester, Minnesota
2000-2001         Instructor of Urology, Mayo Medical School, Rochester, Minnesota
2017-present     Fellowship in Urologic Oncology, David Geffen School of Medicine, Los Angeles, California

Professional Experience
2000-2001         Chief Resident in Urology, Saint Mary’s Hospital, Rochester, Minnesota
2001-2009         Active Staff, Mark Twain St. Joseph’s Hospital, San Andreas, California
2001-2015         Active Staff, Marshall Hospital, Placerville, California
2001-2015         Active Staff, Sutter-Amador Hospital, Jackson, California
2004-2017         Active Staff, Sutter-Amador Surgery Center, Jackson, California
2017-2018         Provisional Staff, Ronald Reagan UCLA Medical Center, Los Angeles, California
2018-present     Active Staff, Ronald Reagan UCLA Medical Center, Los Angeles, California

2001-2012         Amador Surgery Center Inc., Jackson, California.  Founding Partner, Director, Secretary.
2003-2007         Marshall Hospital Surgery Center, LLC, Placerville, California.  Founding Partner, Director.
2006-2015         Sacramento ESL Services, LLC, Sacramento, California.  Partner, Director.


Free Access to abstracts at PubMed 


  1. Simopoulos DN, Ratliff J, Elahi P, Brown M, Waters M, McMahon FG:  Cholesterol levels in 1,084 healthy New Orleans males.  Journal of the Louisiana State Medical Society 1993; 145: 347-351.
  2. Simopoulos DN, Gibbons SJ, Malysz J, Szurszewski JH, Farrugia G, Ritman EL, Moreland RB, Nehra A:  Corporeal structural and vascular micro architecture with X-ray micro computerized tomography in normal and diabetic rabbits: histopathological correlation.  Journal of Urology 2001; 165(5): 1776-1782.
  3. Chang E, Jones TA, Natarajan S, Sharma D, Simopoulos DN, Margolis DJ, Huang J, Dorey FJ, Marks LS: Value of tracking biopsy in men undergoing active surveillance of prostate cancer.  Journal of Urology 2018; 199(1): 98-105.
  4. *Elkhoury FF, *Simopoulos DN, Marks LS:  Targeted Prostate Biopsy in the Era of Active Surveillance.  Urology 2018; 112(2): 12-19. *Co-First Authors.
  5. Elkhoury FF, Simopoulos DN, Marks LS:  MR-Guided Biopsy and Focal Therapy:  The New Era of Prostate Cancer Management.  Current Opinion in Urology 2018; 28(2): 93-101. 


Review Articles
1. Simopoulos DN, Malek RS:  Benign prostatic hyperplasia:  the PSA dilemma and new approaches to therapy.  Contemporary Internal Medicine 1998; 10(1): 42-51.
2. Simopoulos DN, Blute ML:  Transurethral microwave thermotherapy: assessing the value. Contemporary  Urology 2000; 12(12): 30-48.

Case Reports
1. Simopoulos DN, Natarajan S, Jones TA, Fendler WP, Sisk Jr AE, Marks, LS:  Targeted Prostate Biopsy Using 68Gallium PSMA-PET/CT for Image Guidance. Urology Case Reports 2017; 14(3): 11-14.

Book Chapters
1. Simopoulos DN, Blute ML:  Transurethral microwave thermotherapy, in Lepor H. (ed) Prostatic Diseases.  Philadelphia, W.B. Saunders Company, 2000, pp 277-91.

Other Publications:
1. Simopoulos D, Sisk A, Priester A, Kwan L, Reiter R, Marks L:  Targeted cancer core length and risk-  stratification of prostate cancer.  AUA, 2018.
2. Simopoulos D, Delfin M, Kwan L, Priester A, Felker E, Sisk A, Marks L:  Hemi-gland cryoablation of   prostate cancer: use of MRI-guided biopsy for evaluation and follow-up.  AUA, 2018.
3. Simopoulos D, Vandal J, Felker E, Kwan L, Sisk A, Marks L:  Clinical significance of grade 5 lesions on  MRI.  AUA, 2018.




American Urological Association

American Urological Association Western Section Health Policy Committee (2011-2016)

California Medical Association Committee on Insurance and Physician Reimbursement (Chair 2011; Member 2008-2010)
District XI House of Delegates (Delegate 2012, Alternate Delegate 2006-2011)
El Dorado County Representative (2006-2011)

American Association of Clinical UrologistsCalifornia Representative, State Society Network (2011-present)

California Urological Association (Chairman on Legislation 2011-2016)

Sierra Sacramento Valley Medical Association (Director 2010-2012)

CALPAC (Political Action Committee of the CMA) (Director 2011-2012)

Awards & Honors

2000Minnesota Urological Society:  Kelalis Resident’s Essay Competition, First Prize.
2000 American Urological Association:  Essay Contest for Basic Science Research, Co-Third Prize.