The James Buchanan Brady Urological Institute
 
 
 
 Ashley E. Ross, M.D, Ph.D. Ashley E. Ross, MD, PhD
Assistant Professor, Departments of Urology, Oncology and Pathology
Johns Hopkins School of Medicine

Email: aross2@jhmi.edu
         

RESEARCH ACTIVITES


Free Access to abstracts at PubMed

Publications

  1.   Tretter T*, Ross AE*, Dordai DI, Desiderio S.  Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk.  J Exp Med.  2003 Dec 15; 198(12):  1863-73. 
    *Equal contribution first authorship.

  2. Ross AE, Vuica M, Desiderio S.  Overlapping signals for protein degradation and nuclear localization define a role in intrinsic RAG-2 nuclear uptake in dividing cells.  Mol Cell Biol. 2003 Aug;23(15):5308-19.

  3. Jiang H, Ross AE, Desiderio S.  Cell cycle-dependent accumulation in vivo of transposition-competent complexes between recombination signal ends and full-length RAG proteins.  J Biol Chem.  2004 Feb 27;279(9):  8478-86.

  4. Jiang H, Chang FC, Ross AE, Lee J, Nakayama K, Nakayama K, Desiderio S. Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle. Mol Cell  2005 Jun 10;18(6):  699-709.

  5. Ross AE, Handa S, Lingeman JE, Matlaga BR.  Kidney stones during pregnancy:  an investigation into stone composition.  Urol Res.  2008 May; 36(2):  99-102.

  6. Musicki B, Ross AE, Champion HC, Burnett AL, Bivalacqua TJ.  Posttranslational modification of constitutive nitric oxide synthase in the penis.  J Androl 2009 Jul-Aug; 30(4):  352-62.

  7. Loeb S, Epstein JI, Ross AE, Shultz L, Humphreys EB, Jarow JP.  Benign prostate glands at the bladder neck margin in robotic vs open radical prostatectomy.  BJU Int 2010 Mar 25.

  8. Ross AE, Loeb S, Landis P, Partin AW, Epstein JI, Ketterman A, Feng Z, Carter HB, Walsh PC.  Prostate-specific antigen kinetics during follow-up are an unreliable trigger for intervention in a prostate cancer surveillance program.  J Clin Oncol.  2010 Jun 10;28(17):2810-6.

  9. Bivalacqua TJ, Ross AE, Strong TD, Gebska MA, Musicki B, Champion HC, Burnett AL.  Attenuated RhoA/Rho-Kinase signaling in the penis of transgenic sickle cell mice.  Urology. 2010 Aug: 76(2):510.e7-12.


  10. Emadi A, Ross AE, Cowan KM, Fortenberry YM, Vuica-Ross M.  A chemical genetic screen for modulators of asymmetrical 2,2’-dimeric naphthoquinone cytotoxicity in yeast.  PLoS ONE 2010, May 26;5(5):e10846.

  11. Cilip CM, Ross AE, Jarow J, Fried NM.  Application of an optical clearing agent during noninvasive laser coagulation of the canine vas deferens.  J Biomed Opt. 2010 Jul-Aug; 15(4):04001.

  12. Ross AE, Emadi A, Marchionni L, Hurley PJ, Simons BW, Schaeffer EM, Vuica-Ross M.  Dimeric napthoquinones, a novel class of compounds with prostate cancer cytotoxicitiy.  BJU Int.  2010 Dec 22.

  13. Ross AE, Marchionni L, Vuica-Ross M, Cheadle C. Fan J, Berman DM, Schaeffer EM.  Gene expression pathways of high grade localized prostate cancer.  Prostate 2011, Feb 25.

  14. Pierorazio PM, Ross AE, Schaeffer EM, Epstein JI, Han M, Walsh PC, Partin AW.  A contemporary analysis of outcomes of adenocarcinoma of the prostate with seminal vesicle invasion (pT3b) after radical prostatectomy.  J Urol 2011.  May; 185(5):  1691-7.\

  15.  Ross AE, Marchionni L, Phillips TM, Miller RM, Hurley PJ, Simons BW, Salmasi AH, Schaeffer AJ, Gearhart JP, Schaeffer EM.  Molecular effects of genistein on male urethral development.  J. Urol 2011.  May; 185(5):1894-8.

  16.  Loeb S, Feng Z, Ross AE, Trock BJ, Humpreys EB, Walsh PC. Can we stop prostate-specific antigen testing 10 years after radical prostatectomy?  J Urol 2011.  Aug; 186(2):  500-5.

  17.   Pierorazio PM, Ross AE, Han M, Epstein J, Walsh PC, Partin A, Schaeffer EM.  Evolution of the clinical presentation of men undergoing radical prostatectomy for high-risk prostate cancer.  BJUI 2011, Aug 22.

  18. Gupta AD, Bandari J, Ross AE, Tufaro AP, Bivalacqua TJ.  Management of primary aquamouns cell carcinoma at the mucocutaneous junction of an illeal conduit.  Urology.  2011, Sept 9.

  19. Cilip CM, Pierorazio PM, Ross AE, Allaf ME, Fried NM.  High-frequency ultrasound imaging of non-invasive laser coagulation of the canine vas deferens.  Lasers Surg Med.  2011 Sep: 43(8):  838-42.

  20. Emadi A, Le A, Harwood CJ, Stagliano KW, Kamangar F, Ross AE, Cooper CR, Dang CV, Karp JE, Vuica-Ross M.  Metabolic and electrochemical mechanisms of dimeric naphthoquinones in cytotoxicity in breast cancer cells.  Bioorg Med Chem.  2011 Dec 1:  19(23):  7057-62.

  21. Ross AE, Feng Z, Pierorazio PM, Landis P, Walsh PC, Carter HB, Trock BJ, Schaeffer EM.  Effects of treatment with 5-Alpha reductase inhibitors on progression in monitored men with favourable-risk prostate cancer.  BJU Int.  2012 Jan 30.

  22. Pierorazio PM, Ross AE, Lin BM, Epstein JI, Han M, Walsh PC, Partin AW, Pavlovich CP, Schaeffer EM.  Preoperative characteristics of high-Gleason disease predictive of favourable pathological and clinical outcomes at radical prostatectomy.  BJU Int.  2012 Feb28.]

  23. Huang Z, Hurley PJ, Simons BW, Marchionni L, Berman DM, Ross AE, Schaeffer EM.  Sox9 is required for prostate development and prostate cancer initiation.  Oncotarget 2012 Jul 2.


  24. Hurley PJ, Marchionni L, Simons BW, Ross AE, Peskoe SB, Miller RM, Erho N, Vergara IA, Ghadessi M, Huang Z, Gurel B, Park BH, Davicioni E, Jenkins RB, Platz EA, Berman DM, Schaeffer EM.  Secreted protein, acidic and rich in cystein-like 1 (SPARCL1) is down regulated in aggressive prostate cacner and is prognostic for poor clinical outcome.  Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14977-82. Epub 2012 Aug 27.

  25. Simons BW, Hurley PJ, Huang Z, Ross AE, Miller R, Marchionni L, Berman DM, Schaeffer EM.  Wnt signaling through beta-catenin is required for prostate lineage specification.  Dev Biol. 2012 Aug 30.



Review Articles

  1. Vuica M, Ross AE, Nichols JH.  Atypical antipsychotic drugs.  AACC Therapeutic Drug Monitoring and Toxicology.  22(3):66-75,2000.

 

Book Chapters

  1.   Ross AE, Burnett AL.  Anuria and oliguria.  5-Minute Urology Consult, 2nd Ed. 2009.

  2. Ross AE, Burnett AL.  Balanitis and balanoposthitis.  5-Minute Urology Consult, 2nd Ed.  2009.

  3. Ross AE, Bivalacqua TJ.  Bladder Cancer Superficial.  Handbook of Urology.  2012

  4. Ross AE, Bivalacqua TJ.  Invasive Bladder Cancer/Urinary Diversion.  Handbook of Urology.  2012



© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. All rights reserved.| Disclaimer
Email: webmaster@urology.jhu.edu | 600 North Wolfe Street, Baltimore, Maryland 21287